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Jian Chen Selected Research

Vaccines

10/2023Facile preparation of PEGylated polyethylenimine polymers as vaccine carriers with reduced cytotoxicity and enhanced Interleukin-2 (IL-2) production.
8/2023Virus-induced breath biomarkers: A new perspective to study the metabolic responses of COVID-19 vaccinees.
1/2023Rapid construction of infectious clones for distinct Newcastle disease virus genotypes.
10/2022Effectiveness of inactivated and Ad5-nCoV COVID-19 vaccines against SARS-CoV-2 Omicron BA. 2 variant infection, severe illness, and death.
1/2022Severity of COVID-19 after Vaccination among Hemodialysis Patients: An Observational Cohort Study.
1/2022Outcome and effect of vaccination in SARS-CoV-2 Omicron infection in hemodialysis patients: a cohort study.
10/2020Safety of pentavalent DTaP-IPV/Hib combination vaccine in post-marketing surveillance in Guangzhou, China, from 2011 to 2017.
1/2020Comprehensive mutanome analysis of Lewis lung cancer reveals immunogenic neoantigens for therapeutic vaccines.
1/2020Genomic Variability and Post-translational Protein Processing Enhance the Immune Evasion of Mycoplasma hyopneumoniae and Its Interaction With the Porcine Immune System.
4/2019Effects of a 15-amino-acid isoform of amyloid- β expressed by silkworm pupae on B6C3-Tg Alzheimer's disease transgenic mice.
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Jian Chen Research Topics

Disease

441Neoplasms (Cancer)
06/2024 - 02/2003
86Inflammation (Inflammations)
05/2024 - 12/2007
82Neoplasm Metastasis (Metastasis)
03/2024 - 05/2004
69Breast Neoplasms (Breast Cancer)
03/2024 - 10/2002
62Infections
05/2024 - 08/2002
59Hypoxia (Hypoxemia)
02/2024 - 02/2003
57Stroke (Strokes)
02/2024 - 01/2009
50Stomach Neoplasms (Stomach Cancer)
03/2024 - 03/2004
50Carcinogenesis
11/2023 - 05/2010
48Ischemic Stroke
02/2024 - 01/2013
48Glioma (Gliomas)
02/2024 - 05/2002
46Hepatocellular Carcinoma (Hepatoma)
04/2024 - 09/2005
37Colorectal Neoplasms (Colorectal Cancer)
02/2024 - 02/2004
37Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
12/2023 - 11/2010
36COVID-19
10/2023 - 01/2020
34Carcinoma (Carcinomatosis)
12/2023 - 05/2002
29Atrial Fibrillation
07/2023 - 03/2004
29Colonic Neoplasms (Colon Cancer)
01/2022 - 05/2004
27Wounds and Injuries (Trauma)
05/2024 - 08/2006
26Spinal Cord Injuries (Spinal Cord Injury)
03/2024 - 08/2005
24Alzheimer Disease (Alzheimer's Disease)
02/2024 - 03/2010
24Body Weight (Weight, Body)
01/2024 - 08/2007
24Ischemia
01/2024 - 01/2004
22Hemorrhage
06/2023 - 01/2009
22Fibrosis (Cirrhosis)
01/2023 - 07/2010
21Pain (Aches)
01/2024 - 06/2003
21Lung Neoplasms (Lung Cancer)
12/2023 - 09/2009
21Reperfusion Injury
08/2023 - 01/2004
20Adenocarcinoma
03/2024 - 05/2004
20Prostatic Neoplasms (Prostate Cancer)
01/2024 - 02/2005
20Hypertension (High Blood Pressure)
11/2023 - 03/2005
19Brain Ischemia (Cerebral Ischemia)
08/2023 - 01/2003
18Osteosarcoma (Osteogenic Sarcoma)
01/2024 - 01/2005
18Cardiovascular Diseases (Cardiovascular Disease)
11/2023 - 07/2008
18Glioblastoma (Glioblastoma Multiforme)
01/2023 - 01/2004
18Pancreatic Neoplasms (Pancreatic Cancer)
10/2022 - 02/2003
17Myocardial Infarction
04/2024 - 01/2009
17Infarction (Infarctions)
07/2023 - 05/2009
17Thrombosis (Thrombus)
01/2021 - 01/2006
16Melanoma (Melanoma, Malignant)
05/2024 - 05/2002
16Rheumatoid Arthritis
01/2024 - 04/2017
16Insulin Resistance
11/2023 - 07/2007
15Type 2 Diabetes Mellitus (MODY)
02/2022 - 09/2008
15Lymphatic Metastasis
01/2022 - 08/2005
14Non-alcoholic Fatty Liver Disease
05/2023 - 09/2013
13Pneumonia (Pneumonitis)
11/2023 - 07/2008
13Intervertebral Disc Degeneration
03/2023 - 05/2013
12Asthma (Bronchial Asthma)
03/2024 - 12/2005
12Neurodegenerative Diseases (Neurodegenerative Disease)
02/2024 - 05/2014
12Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
08/2023 - 10/2009
12Cognitive Dysfunction
05/2023 - 11/2014
12Osteoarthritis
11/2022 - 03/2015
12Osteoporosis
08/2022 - 10/2008
11Traumatic Brain Injuries (Traumatic Brain Injury)
05/2024 - 03/2011

Drug/Important Bio-Agent (IBA)

175Proteins (Proteins, Gene)FDA Link
02/2024 - 06/2003
93Biomarkers (Surrogate Marker)IBA
04/2024 - 09/2007
67Messenger RNA (mRNA)IBA
01/2023 - 05/2002
55CytokinesIBA
05/2024 - 12/2005
49Therapeutic UsesIBA
05/2024 - 04/2002
48MicroRNAs (MicroRNA)IBA
04/2024 - 09/2010
31Glucose (Dextrose)FDA LinkGeneric
11/2023 - 04/2003
29Long Noncoding RNAIBA
03/2024 - 01/2014
27RNA (Ribonucleic Acid)IBA
12/2023 - 09/2012
27VaccinesIBA
10/2023 - 01/2004
26Reactive Oxygen Species (Oxygen Radicals)IBA
04/2024 - 12/2012
25Indicators and Reagents (Reagents)IBA
10/2023 - 08/2005
24LipidsIBA
01/2024 - 09/2007
23EnzymesIBA
05/2023 - 01/2003
22Neuroprotective AgentsIBA
04/2024 - 05/2009
22AntigensIBA
01/2024 - 01/2002
21Oxygen (Dioxygen)IBA
02/2024 - 02/2007
21Cisplatin (Platino)FDA LinkGeneric
01/2023 - 01/2005
21Interleukin-6 (Interleukin 6)IBA
10/2022 - 01/2003
20Peptides (Polypeptides)IBA
02/2024 - 12/2011
18CollagenIBA
05/2024 - 11/2012
18Estrogen ReceptorsIBA
09/2023 - 11/2010
18Small Interfering RNA (siRNA)IBA
04/2022 - 01/2013
17Phosphotransferases (Kinase)IBA
01/2023 - 09/2005
167,3'-dihydroxy-4'-methoxyisoflavoneIBA
09/2023 - 09/2011
16DNA (Deoxyribonucleic Acid)IBA
01/2023 - 05/2004
13CalciumIBA
03/2024 - 01/2006
13CateninsIBA
12/2023 - 03/2011
13Anti-Bacterial Agents (Antibiotics)IBA
12/2023 - 10/2009
12C-Reactive ProteinIBA
03/2024 - 04/2009
12Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2024 - 05/2005
12Estrogens (Estrogen)FDA Link
01/2022 - 10/2002
12Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
11/2020 - 01/2009
11LipopolysaccharidesIBA
04/2024 - 07/2008

Therapy/Procedure

230Therapeutics
05/2024 - 10/2003
77Drug Therapy (Chemotherapy)
01/2024 - 01/2005
32Immunotherapy
02/2024 - 04/2006
26Thrombectomy
02/2024 - 12/2017
19Radiotherapy
03/2024 - 09/2013
18Chinese Traditional Medicine (Traditional Chinese Medicine)
11/2023 - 04/2007
16Catheter Ablation
07/2023 - 02/2009
15Radiofrequency Ablation
04/2024 - 02/2002
14Catheters
01/2022 - 02/2002
13Transplantation
10/2023 - 01/2010
12Punctures
01/2024 - 03/2007
12Length of Stay
06/2022 - 09/2012